Traumatic Coma RESPONSE Study

The above figure shows several functional MRI techniques that are being used by NICC researchers to identify brain activity in patients with traumatic disorders of consciousness. Figure adapted from Edlow BL, Giacino JT, Wu O. Functional MRI and outcome in traumatic coma. Current Neurology and Neuroscience Reports. 2013;13:375.

RESPONSE (REsting and Stimulus-based Paradigms to detect Organized NetworkS and predict Emergence of consciousness) is an MRI and EEG study of brain network structure and function in patients with acute traumatic coma.

The primary goal of this study is to determine if acute MRI and EEG predict long-term outcomes. 

The secondary goal of this study is to identify longitudinal changes within brain networks that enable recovery of consciousness, communication, and functional independence.