The ascending arousal network (AAN) is a subcortical neural network that is critical to consciousness. To date, the majority of studies investigating AAN connectivity have utilized animal models. As a result, current knowledge about the connectivity of the human AAN is largely based upon extrapolations from animal data.

Ongoing Research StudiesBrian EdlowAugust 21, 2019

Ex Vivo Connectomics of Traumatic Coma

The primary goal of this study is to identify the circuits within the brainstem arousal network that are essential for recovery of consciousness after traumatic coma.

Ongoing Research StudiesBrian EdlowAugust 21, 2019

Traumatic Coma RESPONSE Study

The primary goal of this study is to determine if acute MRI and EEG predict long-term outcomes.

The secondary goal of this study is to identify longitudinal changes within brain networks that enable recovery of consciousness, communication, and functional independence.